Lineage for d3d14a_ (3d14 A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674741Species Mouse (Mus musculus) [TaxId:10090] [187169] (34 PDB entries)
  8. 1674757Domain d3d14a_: 3d14 A: [173610]
    automated match to d1ol5a_
    complexed with ak1

Details for d3d14a_

PDB Entry: 3d14 (more details), 1.9 Å

PDB Description: Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea
PDB Compounds: (A:) serine/threonine kinase 6

SCOPe Domain Sequences for d3d14a_:

Sequence, based on SEQRES records: (download)

>d3d14a_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
gplgskrqwtledfdigrplgkgkfgnvylarerqskfilalkvlfktqlekagvehqlr
reveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklsrfdeqrtatyite
lanalsychskrvihrdikpenlllgsngelkiadfgwsvhapssrrttlcgtldylppe
miegrmhdekvdlwslgvlcyeflvgmppfeahtyqetyrrisrveftfpdfvtegardl
isrllkhnasqrltlaevlehpwikanss

Sequence, based on observed residues (ATOM records): (download)

>d3d14a_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
gplgsrqwtledfdigrplgkgkfgnvylarerqskfilalkvlfktqlekagvehqlrr
eveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklsrfdeqrtatyitel
analsychskrvihrdikpenlllgsngelkiadfgwsvhapscgtldylppemiegrmh
dekvdlwslgvlcyeflvgmppfeahtyqetyrrisrveftfpdfvtegardlisrllkh
nasqrltlaevlehpwikanss

SCOPe Domain Coordinates for d3d14a_:

Click to download the PDB-style file with coordinates for d3d14a_.
(The format of our PDB-style files is described here.)

Timeline for d3d14a_: