Lineage for d3d06a_ (3d06 A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2363595Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2364216Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2364217Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)
  6. 2364218Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)
  7. 2364219Species Human (Homo sapiens) [TaxId:9606] [49420] (63 PDB entries)
  8. 2364220Domain d3d06a_: 3d06 A: [173589]
    automated match to d1gzha_
    complexed with zn; mutant

Details for d3d06a_

PDB Entry: 3d06 (more details), 1.2 Å

PDB Description: Human p53 core domain with hot spot mutation R249S (I)
PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d3d06a_:

Sequence, based on SEQRES records: (download)

>d3d06a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d3d06a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3d06a_:

Click to download the PDB-style file with coordinates for d3d06a_.
(The format of our PDB-style files is described here.)

Timeline for d3d06a_: