Lineage for d3d05a_ (3d05 A:)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2040316Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
    sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold
  4. 2040931Superfamily b.2.5: p53-like transcription factors [49417] (8 families) (S)
  5. 2040932Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)
  6. 2040933Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)
  7. 2040934Species Human (Homo sapiens) [TaxId:9606] [49420] (40 PDB entries)
  8. 2040953Domain d3d05a_: 3d05 A: [173588]
    automated match to d1gzha_
    complexed with zn; mutant

Details for d3d05a_

PDB Entry: 3d05 (more details), 1.7 Å

PDB Description: human p53 core domain with hot spot mutation r249s (ii)
PDB Compounds: (A:) Cellular tumor antigen p53

SCOPe Domain Sequences for d3d05a_:

Sequence, based on SEQRES records: (download)

>d3d05a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstpppgt
rvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfrhs
vvvpyeppevgsdcttihynymcnsscmggmnrspiltiitledssgnllgrnsfevrvc
acpgrdrrteeen

Sequence, based on observed residues (ATOM records): (download)

>d3d05a_ b.2.5.2 (A:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
svpsqktyqgsygfrlgflvtctyspalnkmfcqlaktcpvqlwvdstpppgtrvramai
ykqsqhmtevvrrcphhersdglappqhlirvegnlrveylddrntfrhsvvvpyeppev
gsdcttihynymcnsscmggmnrspiltiitledssgnllgrnsfevrvcacpgrdrrte
een

SCOPe Domain Coordinates for d3d05a_:

Click to download the PDB-style file with coordinates for d3d05a_.
(The format of our PDB-style files is described here.)

Timeline for d3d05a_: