SCOPe 2.08: Domain d3cs9d_: 3cs9 D:

Lineage for d3cs9d_ (3cs9 D:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3cs9d_: 3cs9 D: [173430]
   automated match to d1opja_
   complexed with nil

Details for d3cs9d_

PDB Entry: 3cs9, 2.21 Å

PDB Description: Human ABL kinase in complex with nilotinib

PDB Compounds: (D:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3cs9d_:

Sequence, based on SEQRES records:

>d3cs9d_ d.144.1.7 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesla
ynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelm
racwqwnpsdrpsfaeihqafetmfqes

Sequence, based on observed residues (ATOM records):

>d3cs9d_ d.144.1.7 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dkwemertditmkhklgggqygevyegvwtvavktlkedtmeveeflkeaavmkeikhpn
lvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameylekk
nfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapeslaynkfs
iksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmracwq
wnpsdrpsfaeihqafetmfqes

Timeline for d3cs9d_:

• d3cs9d_ first appeared in SCOPe 2.01
  
• d3cs9d_ appears in SCOPe 2.07