SCOPe 2.01: Domain d3cs9c_: 3cs9 C:

Lineage for d3cs9c_ (3cs9 C:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d3cs9c_: 3cs9 C: [173429]
   automated match to d1opja_
   complexed with nil

Details for d3cs9c_

PDB Entry: 3cs9, 2.21 Å

PDB Description: Human ABL kinase in complex with nilotinib

PDB Compounds: (C:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d3cs9c_:

Sequence, based on SEQRES records:

>d3cs9c_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmk
eikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissam
eylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesl
aynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyel
mracwqwnpsdrpsfaeihqafetmf

Sequence, based on observed residues (ATOM records):

>d3cs9c_ d.144.1.7 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ydkwemertditmkhklgggqygevyegvwkkysltvavktleveeflkeaavmkeikhp
nlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqissameylek
knfihrdlaarnclvgenhlvkvadfgpikwtapeslaynkfsiksdvwafgvllweiat
ygmspypgidlsqvyellekdyrmerpegcpekvyelmracwqwnpsdrpsfaeihqafe
tmf

Timeline for d3cs9c_:

• d3cs9c_ is new in SCOPe 2.01-stable
  
• d3cs9c_ appears in SCOPe 2.02
  
• d3cs9c_ appears in the current release, SCOPe 2.08