Lineage for d3bufa_ (3buf A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2060177Family b.50.1.2: Pepsin-like [50646] (11 protein domains)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2060948Protein automated matches [190156] (4 species)
    not a true protein
  7. 2060973Species Human (Homo sapiens) [TaxId:9606] [187237] (38 PDB entries)
  8. 2061001Domain d3bufa_: 3buf A: [172826]
    automated match to d1fkna_
    complexed with aeg

Details for d3bufa_

PDB Entry: 3buf (more details), 2.3 Å

PDB Description: BACE-1 complexed with compound 2
PDB Compounds: (A:) Beta-secretase 1

SCOPe Domain Sequences for d3bufa_:

Sequence, based on SEQRES records: (download)

>d3bufa_ b.50.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rgsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrq
lsstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnw
egilglayaeiarpddslepffdslvkqthvpnlfslqlcgagfplnqsevlasvggsmi
iggidhslytgslwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlr
lpkkvfeaavasikaasstekfpdgfwlgeqlvcwqagttpwnifpvislylmgevtnqs
fritilpqqylrpvedvatsqddcykfaisqsstgtvmgavimegfyvvfdrarkrigfa
vsachvhdefrtaavegpfvtldmedcgyni

Sequence, based on observed residues (ATOM records): (download)

>d3bufa_ b.50.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rgsfvemvdnlrgksgqgyyvemtvgsppqtlnilvdtgssnfavgaaphpflhryyqrq
lsstyrdlrkgvyvpytqgkwegelgtdlvsiphgpnvtvraniaaitesdkffingsnw
egilglayaeiarpddslepffdslvkqthvpnlfslqlcgsvggsmiiggidhslytgs
lwytpirrewyyeviivrveingqdlkmdckeynydksivdsgttnlrlpkkvfeaavas
ikaassfpdgfwlgeqlvcwqawnifpvislylmgevtnqsfritilpqqylrpvdcykf
aisqsstgtvmgavimegfyvvfdrarkrigfavsachrtaavegpfvtldmedcgyni

SCOPe Domain Coordinates for d3bufa_:

Click to download the PDB-style file with coordinates for d3bufa_.
(The format of our PDB-style files is described here.)

Timeline for d3bufa_: