SCOPe 2.02: Domain d3bpfc_: 3bpf C:

Lineage for d3bpfc_ (3bpf C:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (23 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.1: Papain-like [54002] (26 proteins)

6. Protein Falcipain 2 [142846] (1 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142847] (5 PDB entries)
   Uniprot Q9N6S8 244-484

8. Domain d3bpfc_: 3bpf C: [172769]
   automated match to d1yvba1
   complexed with e64, gol

Details for d3bpfc_

PDB Entry: 3bpf, 2.9 Å

PDB Description: Crystal Structure of Falcipain-2 with Its inhibitor, E64

PDB Compounds: (C:) Cysteine protease falcipain-2

SCOPe Domain Sequences for d3bpfc_:

Sequence, based on SEQRES records:

>d3bpfc_ d.3.1.1 (C:) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
mnyeevikkyrgeenfdhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairknk
litlseqelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrcte
kygiknylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvgf
gmkeivnpltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafiplie

Sequence, based on observed residues (ATOM records):

>d3bpfc_ d.3.1.1 (C:) Falcipain 2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
mnyeevikkydhaaydwrlhsgvtpvkdqkncgscwafssigsvesqyairknklitlse
qelvdcsfknygcngglinnafedmielggicpdgdypyvsdapnlcnidrctekygikn
ylsvpdnklkealrflgpisisvavsddfafykegifdgecgdqlnhavmlvgfgmkeiv
npltkkgekhyyyiiknswgqqwgergfinietdesglmrkcglgtdafiplie

Timeline for d3bpfc_:

• d3bpfc_ first appeared in SCOPe 2.01
  
• d3bpfc_ appears in SCOPe 2.03
  
• d3bpfc_ appears in the current release, SCOPe 2.08