SCOPe 2.08: Domain d3beaa_: 3bea A:

Lineage for d3beaa_ (3bea A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3beaa_: 3bea A: [172570]
   automated match to d1t45a_
   complexed with ixh, so4

Details for d3beaa_

PDB Entry: 3bea, 2.02 Å

PDB Description: cfms tyrosine kinase (tie2 kid) in complex with a pyrimidinopyridone inhibitor

PDB Compounds: (A:) Macrophage colony-stimulating factor 1 receptor

SCOPe Domain Sequences for d3beaa_:

Sequence, based on SEQRES records:

>d3beaa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafglgk
edavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlviteyc
cygdllnflrrksrvletdpafaianstlstrdllhfssqvaqgmaflaskncihrdvaa
rnvlltnghvakigdfglardimndsnyivkgnarlpvkwmapesifdcvytvqsdvwsy
gillweifslglnpypgilvnskfyklvkdgyqmaqpafapkniysimqacwalepthrp
tfqqicsflqeqaqedrrer

Sequence, based on observed residues (ATOM records):

>d3beaa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qvrwkiiesyegnsytfidptqlpynekwefprnnlqfgktlgagafgkvveatafglgk
edavlkvavkmlkstahadekealmselkimshlgqhenivnllgacthggpvlviteyc
cygdllnflrrksrvlstlstrdllhfssqvaqgmaflaskncihrdvaarnvlltnghv
akigdfglardimndsnyivkgnarlpvkwmapesifdcvytvqsdvwsygillweifsl
glnpypgilvnskfyklvkdgyqmaqpafapkniysimqacwalepthrptfqqicsflq
eqaqedrrer

Timeline for d3beaa_:

• d3beaa_ first appeared in SCOPe 2.01
  
• d3beaa_ appears in SCOPe 2.07