SCOPe 2.06: Domain d3ax8a_: 3ax8 A:

Lineage for d3ax8a_ (3ax8 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48529] (28 PDB entries)

8. Domain d3ax8a_: 3ax8 A: [172369]
   automated match to d1ie9a_
   complexed with eim

Details for d3ax8a_

PDB Entry: 3ax8, 2.6 Å

PDB Description: crystal structure of the human vitamin d receptor ligand binding domain complexed with 15alpha-methoxy-1alpha,25-dihydroxyvitamin d3

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d3ax8a_:

Sequence, based on SEQRES records:

>d3ax8a_ a.123.1.1 (A:) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlp
hladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtc
gnqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqd
aalieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqp
ecsmkltplvlevfg

Sequence, based on observed residues (ATOM records):

>d3ax8a_ a.123.1.1 (A:) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgsvtlelsqlsmlphl
adlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcgn
qdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaa
lieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqpec
smkltplvlevfg

Timeline for d3ax8a_:

• d3ax8a_ first appeared in SCOPe 2.01
  
• d3ax8a_ appears in SCOPe 2.05
  
• d3ax8a_ appears in SCOPe 2.07
  
• d3ax8a_ appears in the current release, SCOPe 2.08