SCOPe 2.05: Domain d3adsa_: 3ads A:

Lineage for d3adsa_ (3ads A:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (138 PDB entries)

8. Domain d3adsa_: 3ads A: [172013]
   automated match to d1nyxa_
   protein/DNA complex; complexed with imn

Details for d3adsa_

PDB Entry: 3ads, 2.25 Å

PDB Description: Human PPARgamma ligand-binding domain in complex with indomethacin

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3adsa_:

Sequence, based on SEQRES records:

>d3adsa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d3adsa_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
kevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktetdmslhpllqeiykdl

Timeline for d3adsa_:

• d3adsa_ first appeared in SCOPe 2.01
  
• d3adsa_ appears in SCOPe 2.04
  
• d3adsa_ appears in SCOPe 2.06
  
• d3adsa_ appears in the current release, SCOPe 2.08