SCOPe 2.08: Domain d3a2ja_: 3a2j A:

Lineage for d3a2ja_ (3a2j A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48529] (30 PDB entries)

8. Domain d3a2ja_: 3a2j A: [171660]
   automated match to d1ie9a_
   protein/DNA complex; complexed with tej

Details for d3a2ja_

PDB Entry: 3a2j, 2.7 Å

PDB Description: crystal structure of the human vitamin d receptor (h305f/h397f) ligand binding domain complexed with tei-9647

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d3a2ja_:

Sequence, based on SEQRES records:

>d3a2ja_ a.123.1.1 (A:) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlp
hladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtc
gnqdykyrvsdvtkagfslelieplikfqvglkklnlheeehvllmaicivspdrpgvqd
aalieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneefskqyrclsfqp
ecsmkltplvlevfg

Sequence, based on observed residues (ATOM records):

>d3a2ja_ a.123.1.1 (A:) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
dslrpklseeqqriiailldahhktydptysdfcqfrppvrvndgsvtlelsqlsmlphl
adlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcgn
qdykyrvsdvtkagfslelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaa
lieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneefskqyrclsfqpec
smkltplvlevfg

Timeline for d3a2ja_:

• d3a2ja_ first appeared in SCOPe 2.01
  
• d3a2ja_ appears in SCOPe 2.07