SCOPe 2.01: Domain d2zy0a_: 2zy0 A:

Lineage for d2zy0a_ (2zy0 A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (32 PDB entries)
   Uniprot P19793 227-458

8. Domain d2zy0a_: 2zy0 A: [171603]
   automated match to d1lbda_
   complexed with 21p

Details for d2zy0a_

PDB Entry: 2zy0, 2.9 Å

PDB Description: crystal structure of the human rxr alpha ligand binding domain bound to a synthetic agonist compound and a coactivator peptide

PDB Compounds: (A:) Retinoic acid receptor RXR-alpha

SCOPe Domain Sequences for d2zy0a_:

Sequence, based on SEQRES records:

>d2zy0a_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d2zy0a_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
nedmpverileaelavepndpvtnicqaadkqlftlvewakriphfselplddqvillra
gwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmqmd
ktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllrlp
alrsiglkclehlfffkligdtpidtflmemleap

Timeline for d2zy0a_:

• d2zy0a_ is new in SCOPe 2.01-stable
  
• d2zy0a_ appears in SCOPe 2.02
  
• d2zy0a_ appears in the current release, SCOPe 2.08