SCOPe 2.08: Domain d2zxna_: 2zxn A:

Lineage for d2zxna_ (2zxn A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [101432] (25 PDB entries)

8. Domain d2zxna_: 2zxn A: [171567]
   automated match to d1rkha_
   protein/DNA complex; complexed with jc1

Details for d2zxna_

PDB Entry: 2zxn, 2.1 Å

PDB Description: A New Class of Vitamin D Receptor Ligands that Induce Structural Rearrangement of the Ligand-binding Pocket

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d2zxna_:

Sequence, based on SEQRES records:

>d2zxna_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrmdgstgsvtldlsplsmlphladl
vsysiqkvigfakmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdy
kydvtdvskaghtlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklve
aiqdrlsntlqtyircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmk
ltplvlevfgn

Sequence, based on observed residues (ATOM records):

>d2zxna_ a.123.1.1 (A:) Vitamin D nuclear receptor {Norway rat (Rattus norvegicus) [TaxId: 10116]}
klseeqqhiiailldahhktydptyadfrdfrppvrmsplsmlphladlvsysiqkvigf
akmipgfrdltsddqivllkssaievimlrsnqsftmddmswdcgsqdykydvtdvskag
htlelieplikfqvglkklnlheeehvllmaicivspdrpgvqdaklveaiqdrlsntlq
tyircrhpppgshqlyakmiqkladlrslneehskqyrslsfqpensmkltplvlevfgn

Timeline for d2zxna_:

• d2zxna_ first appeared in SCOPe 2.01
  
• d2zxna_ appears in SCOPe 2.07