SCOPe 2.03: Domain d2ztha_: 2zth A:

Lineage for d2ztha_ (2zth A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.1: COMT-like [53336] (4 proteins)

6. Protein automated matches [190251] (3 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187033] (20 PDB entries)

8. Domain d2ztha_: 2zth A: [171501]
   automated match to d1h1da_
   complexed with mg, sam

Details for d2ztha_

PDB Entry: 2zth, 2.6 Å

PDB Description: Crystal structure of holo form of rat catechol-o-methyltransferase

PDB Compounds: (A:) Catechol O-methyltransferase

SCOPe Domain Sequences for d2ztha_:

Sequence, based on SEQRES records:

>d2ztha_ c.66.1.1 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmemnpdyaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssyleymkvvdglekaiyqg

Sequence, based on observed residues (ATOM records):

>d2ztha_ c.66.1.1 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dtkeqrilryvqqnakpgdpqsvleaidtyctqvgdakgqimdavireyspslvlelgay
cgysavrmarllqpgarlltmemnpdyaaitqqmlnfaglqdkvtilngasqdlipqlkk
kydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflayvrgsss
fecthyssyleymkvvdglekaiyqg

Timeline for d2ztha_:

• d2ztha_ first appeared in SCOPe 2.01
  
• d2ztha_ appears in SCOPe 2.02
  
• d2ztha_ appears in SCOPe 2.04
  
• d2ztha_ appears in the current release, SCOPe 2.08