SCOPe 2.03: Domain d2z60a_: 2z60 A:

Lineage for d2z60a_ (2z60 A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187169] (30 PDB entries)

8. Domain d2z60a_: 2z60 A: [171065]
   automated match to d1opjb_
   complexed with p3y; mutant

Details for d2z60a_

PDB Entry: 2z60, 1.95 Å

PDB Description: crystal structure of the t315i mutant of abl kinase bound with ppy-a

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2z60a_:

Sequence, based on SEQRES records:

>d2z60a_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
gspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkea
avmkeikhpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevsavvllymatqi
ssameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwta
peslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpek
vyelmracwqwnpsdrpsfaeihqafetmfqessisdevekelg

Sequence, based on observed residues (ATOM records):

>d2z60a_ d.144.1.7 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
gspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkeeveeflkeaavm
keikhpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevsavvllymatqissa
meylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapes
laynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvye
lmracwqwnpsdrpsfaeihqafetmfqessisdevekelg

Timeline for d2z60a_:

• d2z60a_ first appeared in SCOPe 2.01
  
• d2z60a_ appears in SCOPe 2.02
  
• d2z60a_ appears in SCOPe 2.04
  
• d2z60a_ appears in the current release, SCOPe 2.08, called d2z60a1