SCOPe 2.01: Domain d2yela_: 2yel A:

Lineage for d2yela_ (2yel A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (22 PDB entries)

8. Domain d2yela_: 2yel A: [170766]
   automated match to d1jm4b_
   complexed with edo, wsh

Details for d2yela_

PDB Entry: 2yel, 1.65 Å

PDB Description: crystal structure of the first bromodomain of human brd4 with the inhibitor gw841819x

PDB Compounds: (A:) human brd4

SCOPe Domain Sequences for d2yela_:

Sequence; same for both SEQRES and ATOM records:

>d2yela_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d2yela_:

• d2yela_ is new in SCOPe 2.01-stable
  
• d2yela_ appears in SCOPe 2.02
  
• d2yela_ appears in the current release, SCOPe 2.08, called d2yela1