Lineage for d2ydjb_ (2ydj B:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2218680Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
    CaMK group; CAMKL subfamily; serine/threonine kinase
  7. 2218681Species Human (Homo sapiens) [TaxId:9606] [64405] (66 PDB entries)
  8. 2218707Domain d2ydjb_: 2ydj B: [170764]
    automated match to d1ia8a_
    complexed with po4, ydj

Details for d2ydjb_

PDB Entry: 2ydj (more details), 1.85 Å

PDB Description: discovery of checkpoint kinase inhibitor azd7762 by structure based design and optimization of thiophene carboxamide ureas
PDB Compounds: (B:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d2ydjb_:

Sequence, based on SEQRES records: (download)

>d2ydjb_ d.144.1.7 (B:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2ydjb_ d.144.1.7 (B:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2ydjb_:

Click to download the PDB-style file with coordinates for d2ydjb_.
(The format of our PDB-style files is described here.)

Timeline for d2ydjb_: