Lineage for d2y5le_ (2y5l E:)

  1. Root: SCOPe 2.03
  2. 1449807Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)
  3. 1451563Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
    N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet
  4. 1451564Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families) (S)
  5. 1451565Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)
  6. 1451768Protein automated matches [190281] (4 species)
    not a true protein
  7. 1451772Species Human (Homo sapiens) [TaxId:9606] [187709] (16 PDB entries)
  8. 1451808Domain d2y5le_: 2y5l E: [170627]
    automated match to d1ftaa_
    complexed with ro8

Details for d2y5le_

PDB Entry: 2y5l (more details), 2.2 Å

PDB Description: orally active aminopyridines as inhibitors of tetrameric fructose 1,6-bisphosphatase
PDB Compounds: (E:) Fructose-1,6-bisphosphatase 1

SCOPe Domain Sequences for d2y5le_:

Sequence, based on SEQRES records: (download)

>d2y5le_ e.7.1.1 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagstnvtgd
qvkkldvlsndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidc
lvsvgtifgiyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldp
aigefilvdkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldvipt
dihqrapvilgspddvleflkvyekhsa

Sequence, based on observed residues (ATOM records): (download)

>d2y5le_ e.7.1.1 (E:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagvkkldvl
sndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidclvsvgtif
giyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldpaigefilv
dkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsmvadvhrtl
vyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldviptdihqrapv
ilgspddvleflkvyekhsa

SCOPe Domain Coordinates for d2y5le_:

Click to download the PDB-style file with coordinates for d2y5le_.
(The format of our PDB-style files is described here.)

Timeline for d2y5le_: