SCOPe 2.01: Domain d2xxic_: 2xxi C:

Lineage for d2xxic_ (2xxi C:)

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.94: Periplasmic binding protein-like II [53849] (1 superfamily)
   consists of two similar intertwined domain with 3 layers (a/b/a) each: duplication
   mixed beta-sheet of 5 strands, order 21354; strand 5 is antiparallel to the rest

4. Superfamily c.94.1: Periplasmic binding protein-like II [53850] (4 families)
   Similar in architecture to the superfamily I but partly differs in topology

5. Family c.94.1.1: Phosphate binding protein-like [53851] (41 proteins)

6. Protein Glutamate receptor ligand binding core [53881] (5 species)

7. Species Rat (Rattus norvegicus), GluR2 [TaxId:10116] [53882] (101 PDB entries)

8. Domain d2xxic_: 2xxi C: [170471]
   automated match to d1lbcb_
   complexed with glu, jac, so4, zn

Details for d2xxic_

PDB Entry: 2xxi, 1.6 Å

PDB Description: crystal structure of 1-((4-(3-(trifluoromethyl)-6,7-dihydropyrano(4,3 -c(pyrazol-1(4h)-yl)phenyl)methyl)-2-pyrrolidinone in complex with the ligand binding domain of the rat glua2 receptor and glutamate at 1.6a resolution.

PDB Compounds: (C:) Glutamate receptor 2

SCOPe Domain Sequences for d2xxic_:

Sequence; same for both SEQRES and ATOM records:

>d2xxic_ c.94.1.1 (C:) Glutamate receptor ligand binding core {Rat (Rattus norvegicus), GluR2 [TaxId: 10116]}
nktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyg
ardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpie
saedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvr
kskgkyayllestmneyieqrkpcdtmkvggnldskgygiatpkgsslgnavnlavlkls
eqglldklknkwwydkgecg

Timeline for d2xxic_:

• d2xxic_ is new in SCOPe 2.01-stable
  
• d2xxic_ appears in SCOPe 2.02
  
• d2xxic_ appears in the current release, SCOPe 2.08