SCOPe 2.06: Domain d2xrua_: 2xru A:

Lineage for d2xrua_ (2xru A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d2xrua_: 2xru A: [170333]
   automated match to d1ol7a_
   complexed with 400

Details for d2xrua_

PDB Entry: 2xru, 2.9 Å

PDB Description: aurora-a t288e complexed with pha-828300

PDB Compounds: (A:) serine/threonine-protein kinase 6

SCOPe Domain Sequences for d2xrua_:

Sequence, based on SEQRES records:

>d2xrua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhapssrrtelcgtldylppemiegrm
hdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllk
hnpsqrpmlrevlehpwitanssk

Sequence, based on observed residues (ATOM records):

>d2xrua_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvcgtldylppemiegrmhdekvdlwsl
gvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpmlr
evlehpwitanssk

Timeline for d2xrua_:

• d2xrua_ first appeared in SCOPe 2.01
  
• d2xrua_ appears in SCOPe 2.05
  
• d2xrua_ appears in SCOPe 2.07
  
• d2xrua_ appears in the current release, SCOPe 2.08