SCOPe 2.06: Domain d2xr0a_: 2xr0 A:

Lineage for d2xr0a_ (2xr0 A:)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)

6. Protein beta-Lactamase, class A [56606] (16 species)

7. Species Escherichia coli, TOHO-1 [TaxId:562] [56608] (26 PDB entries)

8. Domain d2xr0a_: 2xr0 A: [170303]
   automated match to d1iysa_
   complexed with so4; mutant

Details for d2xr0a_

PDB Entry: 2xr0, 2.2 Å

PDB Description: room temperature x-ray structure of the perdeuterated toho-1 r274n r276n double mutant beta-lactamase

PDB Compounds: (A:) Toho-1 beta-lactamase

SCOPe Domain Sequences for d2xr0a_:

Sequence; same for both SEQRES and ATOM records:

>d2xr0a_ e.3.1.1 (A:) beta-Lactamase, class A {Escherichia coli, TOHO-1 [TaxId: 562]}
svqqqlealekssggrlgvalintadnsqilyraderfamcstskvmaaaavlkqsesdk
hllnqrveikksdlvnynpiaekhvngtmtlaelgaaalqysdntamnkliahlggpdkv
tafarslgdetfrldrteptlntaipgdprdtttplamaqtlknltlgkalaetqraqlv
twlkgnttgsasiraglpkswvvgdktgsgdygttndiaviwpenhaplvlvtyftqpeq
kaenrndilaaaakivthgf

Timeline for d2xr0a_:

• d2xr0a_ first appeared in SCOPe 2.01
  
• d2xr0a_ appears in SCOPe 2.05
  
• d2xr0a_ appears in SCOPe 2.07
  
• d2xr0a_ appears in the current release, SCOPe 2.08