SCOPe 2.05: Domain d2xmca_: 2xmc A:

Lineage for d2xmca_ (2xmc A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein automated matches [190065] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186857] (38 PDB entries)

8. Domain d2xmca_: 2xmc A: [170224]
   automated match to d1p0ia_
   complexed with cl, f, k, nag, so4, unx; mutant

Details for d2xmca_

PDB Entry: 2xmc, 2.4 Å

PDB Description: g117h mutant of human butyrylcholinesterase in complex with fluoride anion

PDB Compounds: (A:) cholinesterase

SCOPe Domain Sequences for d2xmca_:

Sequence; same for both SEQRES and ATOM records:

>d2xmca_ c.69.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
diiiatkngkvrgmqltvfggtvtaflgipyaqpplgrlrfkkpqsltkwsdiwnatkya
nsccqnidqsfpgfhgsemwnpntdlsedclylnvwipapkpknatvliwiygghfqtgt
sslhvydgkflarvervivvsmnyrvgalgflalpgnpeapgnmglfdqqlalqwvqkni
aafggnpksvtlfgesagaasvslhllspgshslftrailqsgsfnapwavtslyearnr
tlnlakltgcsreneteiikclrnkdpqeillneafvvpygtplsvnfgptvdgdfltdm
pdillelgqfkktqilvgvnkdegtaflvygapgfskdnnsiitrkefqeglkiffpgvs
efgkesilfhytdwvddqrpenyrealgdvvgdynficpaleftkkfsewgnnaffyyfe
hrssklpwpewmgvmhgyeiefvfglplerrdqytkaeeilsrsivkrwanfakygnpqe
tqnqstswpvfksteqkyltlntestrimtklraqqcrfwtsffpkv

Timeline for d2xmca_:

• d2xmca_ first appeared in SCOPe 2.01
  
• d2xmca_ appears in SCOPe 2.04
  
• d2xmca_ appears in SCOPe 2.06
  
• d2xmca_ appears in the current release, SCOPe 2.08