SCOPe 2.04: Domain d2xixa_: 2xix A:

Lineage for d2xixa_ (2xix A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)

8. Domain d2xixa_: 2xix A: [170122]
   automated match to d1xqza_
   complexed with xix

Details for d2xixa_

PDB Entry: 2xix, 2.4 Å

PDB Description: protein kinase pim-1 in complex with fragment-1 from crystallographic fragment screen

PDB Compounds: (A:) Proto-oncogene serine/threonine-protein kinase Pim-1

SCOPe Domain Sequences for d2xixa_:

Sequence; same for both SEQRES and ATOM records:

>d2xixa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
plesqyqvgpllgsggfgsvysgirvsdnlpvaikhvekdrisdwgelpngtrvpmevvl
lkkvssgfsgvirlldwferpdsfvlilerpepvqdlfdfitergalqeelarsffwqvl
eavrhchncgvlhrdikdenilidlnrgelklidfgsgallkdtvytdfdgtrvysppew
iryhryhgrsaavwslgillydmvcgdipfehdeeiirgqvffrqrvssecqhlirwcla
lrpsdrptfeeiqnhpwmqdvllpqetaeihlhs

Timeline for d2xixa_:

• d2xixa_ first appeared in SCOPe 2.01
  
• d2xixa_ appears in SCOPe 2.03
  
• d2xixa_ appears in SCOPe 2.05
  
• d2xixa_ appears in the current release, SCOPe 2.08