Lineage for d2xeza_ (2xez A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1221476Protein automated matches [190091] (10 species)
    not a true protein
  7. 1221597Species Human (Homo sapiens) [TaxId:9606] [188447] (293 PDB entries)
  8. 1221768Domain d2xeza_: 2xez A: [170076]
    automated match to d1ia8a_
    protein/DNA complex; complexed with edo, xez

Details for d2xeza_

PDB Entry: 2xez (more details), 2.25 Å

PDB Description: crystal structure of checkpoint kinase 1 (chk1) in complex with inhibitors
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d2xeza_:

Sequence, based on SEQRES records: (download)

>d2xeza_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
edwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhen
vvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigi
thrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefha
epvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkil
venpsaritipdikkdrwynkplk

Sequence, based on observed residues (ATOM records): (download)

>d2xeza_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
edwdlvqtlgevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfyghrreiqy
lfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenlllder
dnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgivltam
lagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritipdikk
drwynkplk

SCOPe Domain Coordinates for d2xeza_:

Click to download the PDB-style file with coordinates for d2xeza_.
(The format of our PDB-style files is described here.)

Timeline for d2xeza_: