SCOPe 2.01: Domain d2xeya_: 2xey A:

Lineage for d2xeya_ (2xey A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (254 PDB entries)

8. Domain d2xeya_: 2xey A: [170075]
   automated match to d1ia8a_
   protein/DNA complex; complexed with yvq

Details for d2xeya_

PDB Entry: 2xey, 2.7 Å

PDB Description: crystal structure of checkpoint kinase 1 (chk1) in complex with inhibitors

PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d2xeya_:

Sequence, based on SEQRES records:

>d2xeya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhe
nvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgig
ithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefh
aepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhki
lvenpsaritipdikkdrwynkpl

Sequence, based on observed residues (ATOM records):

>d2xeya_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlggevqlavnrvteeavavkivdenikkeicinkmlnhenvvkfyghrreg
niqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpenll
lderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscgiv
ltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsaritip
dikkdrwynkpl

Timeline for d2xeya_:

• d2xeya_ is new in SCOPe 2.01-stable
  
• d2xeya_ appears in SCOPe 2.02
  
• d2xeya_ appears in the current release, SCOPe 2.08