SCOPe 2.04: Domain d2xe8a_: 2xe8 A:

Lineage for d2xe8a_ (2xe8 A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.86: Phosphoglycerate kinase [53747] (1 superfamily)
   consists of two non-similar domains, 3 layers (a/b/a) each
   Domain 1 has parallel beta-sheet of 6 strands, order 342156
   Domain 2 has parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.86.1: Phosphoglycerate kinase [53748] (2 families)

5. Family c.86.1.1: Phosphoglycerate kinase [53749] (2 proteins)
   Domain 2 binds ATP
   automatically mapped to Pfam PF00162

6. Protein automated matches [190709] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188478] (19 PDB entries)

8. Domain d2xe8a_: 2xe8 A: [170062]
   automated match to d1kf0a_
   complexed with 3pg, acp

Details for d2xe8a_

PDB Entry: 2xe8, 1.79 Å

PDB Description: the complete reaction cycle of human phosphoglycerate kinase: the open ternary complex with 3pg and amp-pnp

PDB Compounds: (A:) Phosphoglycerate kinase 1

SCOPe Domain Sequences for d2xe8a_:

Sequence; same for both SEQRES and ATOM records:

>d2xe8a_ c.86.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlmshl
grpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenlrf
hveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlpqk
aggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftf
lkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatva
sgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkats
rgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

Timeline for d2xe8a_:

• d2xe8a_ first appeared in SCOPe 2.01
  
• d2xe8a_ appears in SCOPe 2.03
  
• d2xe8a_ appears in SCOPe 2.05
  
• d2xe8a_ appears in the current release, SCOPe 2.08