SCOPe 2.01: Domain d2x7sa_: 2x7s A:

Lineage for d2x7sa_ (2x7s A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
   single sheet; 10 strands

4. Superfamily b.74.1: Carbonic anhydrase [51069] (2 families)

5. Family b.74.1.1: Carbonic anhydrase [51070] (2 proteins)

6. Protein Carbonic anhydrase [51071] (10 species)

7. Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (370 PDB entries)
   Uniprot P00918

8. Domain d2x7sa_: 2x7s A: [169923]
   automated match to d1cana_
   complexed with gol, wzc, zn

Details for d2x7sa_

PDB Entry: 2x7s, 1.64 Å

PDB Description: structures of human carbonic anhydrase ii inhibitor complexes reveal a second binding site for steroidal and non-steroidal inhibitors.

PDB Compounds: (A:) Carbonic anhydrase 2

SCOPe Domain Sequences for d2x7sa_:

Sequence, based on SEQRES records:

>d2x7sa_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasfk

Sequence, based on observed residues (ATOM records):

>d2x7sa_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhwn
tkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgll
pesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdnw
rpaqplknrqikasfk

Timeline for d2x7sa_:

• d2x7sa_ is new in SCOPe 2.01-stable
  
• d2x7sa_ appears in SCOPe 2.02
  
• d2x7sa_ appears in the current release, SCOPe 2.08