SCOPe 2.06: Domain d2x4ne1: 2x4n E:1-99

Lineage for d2x4ne1 (2x4n E:1-99)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (424 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d2x4ne1: 2x4n E:1-99 [169864]
   Other proteins in same PDB: d2x4nb2, d2x4ne2
   automated match to d1a9bb_
   complexed with gol, mes

Details for d2x4ne1

PDB Entry: 2x4n, 2.34 Å

PDB Description: crystal structure of mhc class i hla-a2.1 bound to residual fragments of a photocleavable peptide that is cleaved upon uv-light treatment

PDB Compounds: (E:) Beta-2-microglobulin

SCOPe Domain Sequences for d2x4ne1:

Sequence; same for both SEQRES and ATOM records:

>d2x4ne1 b.1.1.2 (E:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d2x4ne1:

• d2x4ne1 first appeared in SCOPe 2.01, called d2x4ne_
  
• d2x4ne1 was called d2x4ne_ in SCOPe 2.05
  
• d2x4ne1 appears in SCOPe 2.07
  
• d2x4ne1 appears in the current release, SCOPe 2.08