SCOPe 2.08: Domain d2x2rc_: 2x2r C:

Lineage for d2x2rc_ (2x2r C:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (5 proteins)

6. Protein automated matches [190129] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187145] (33 PDB entries)

8. Domain d2x2rc_: 2x2r C: [169833]
   automated match to d1q0bb_
   complexed with adp, mg, x2o

Details for d2x2rc_

PDB Entry: 2x2r, 2.2 Å

PDB Description: crystal structure of human kinesin eg5 in complex with (r)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid

PDB Compounds: (C:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d2x2rc_:

Sequence, based on SEQRES records:

>d2x2rc_ c.37.1.9 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyresklt
rilqdslggrtrtsiiatispaslnleetlstleyahraknilnkp

Sequence, based on observed residues (ATOM records):

>d2x2rc_ c.37.1.9 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
niqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgastk
qidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiip
rtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviik
gleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelvk
igklnlvdlagsennqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiia
tispaslnleetlstleyahraknilnkp

Timeline for d2x2rc_:

• d2x2rc_ first appeared in SCOPe 2.01
  
• d2x2rc_ appears in SCOPe 2.07