SCOPe 2.06: Domain d2wzda_: 2wzd A:

Lineage for d2wzda_ (2wzd A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.86: Phosphoglycerate kinase [53747] (1 superfamily)
   consists of two non-similar domains, 3 layers (a/b/a) each
   Domain 1 has parallel beta-sheet of 6 strands, order 342156
   Domain 2 has parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.86.1: Phosphoglycerate kinase [53748] (2 families)

5. Family c.86.1.1: Phosphoglycerate kinase [53749] (2 proteins)
   Domain 2 binds ATP
   automatically mapped to Pfam PF00162

6. Protein automated matches [190709] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188478] (22 PDB entries)

8. Domain d2wzda_: 2wzd A: [169726]
   automated match to d1kf0a_
   complexed with 3pg, adp, af3, cl, mg; mutant

Details for d2wzda_

PDB Entry: 2wzd, 1.56 Å

PDB Description: the catalytically active fully closed conformation of human phosphoglycerate kinase k219a mutant in complex with adp, 3pg and aluminium trifluoride

PDB Compounds: (A:) Phosphoglycerate kinase 1

SCOPe Domain Sequences for d2wzda_:

Sequence, based on SEQRES records:

>d2wzda_ c.86.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
rfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlp
qkaggflmkkelnyfakalesperpflailggakvadaiqlinnmldkvnemiigggmaf
tflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqat
vasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvka
tsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

Sequence, based on observed residues (ATOM records):

>d2wzda_ c.86.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
rfhveeegkgepakieafraslsklgdvyvndafgtahrahssmvgvnlpqkaggflmkk
elnyfakalesperpflailggakvadaiqlinnmldkvnemiigggmaftflkvlnnme
igtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatvasgipagwm
gldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkatsrgcitiig
ggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

Timeline for d2wzda_:

• d2wzda_ first appeared in SCOPe 2.01
  
• d2wzda_ appears in SCOPe 2.05
  
• d2wzda_ appears in SCOPe 2.07
  
• d2wzda_ appears in the current release, SCOPe 2.08