SCOPe 2.03: Domain d2wzca_: 2wzc A:

Lineage for d2wzca_ (2wzc A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.86: Phosphoglycerate kinase [53747] (1 superfamily)
   consists of two non-similar domains, 3 layers (a/b/a) each
   Domain 1 has parallel beta-sheet of 6 strands, order 342156
   Domain 2 has parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.86.1: Phosphoglycerate kinase [53748] (2 families)

5. Family c.86.1.1: Phosphoglycerate kinase [53749] (2 proteins)
   Domain 2 binds ATP
   automatically mapped to Pfam PF00162

6. Protein automated matches [190709] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188478] (18 PDB entries)

8. Domain d2wzca_: 2wzc A: [169725]
   automated match to d1kf0a_
   complexed with 3pg, adp, alf, cl, mg

Details for d2wzca_

PDB Entry: 2wzc, 1.5 Å

PDB Description: the catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp, 3pg and aluminium tetrafluoride

PDB Compounds: (A:) Phosphoglycerate kinase 1

SCOPe Domain Sequences for d2wzca_:

Sequence, based on SEQRES records:

>d2wzca_ c.86.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
rfhveeegkgkdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvnlp
qkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaf
tflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqat
vasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvka
tsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

Sequence, based on observed residues (ATOM records):

>d2wzca_ c.86.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
rfhveeegkgepakieafraslsklgdvyvndafgtahrahssmvgvnlpqkaggflmkk
elnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftflkvlnnme
igtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatvasgipagwm
gldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkatsrgcitiig
ggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

Timeline for d2wzca_:

• d2wzca_ first appeared in SCOPe 2.01
  
• d2wzca_ appears in SCOPe 2.02
  
• d2wzca_ appears in SCOPe 2.04
  
• d2wzca_ appears in the current release, SCOPe 2.08