SCOPe 2.07: Domain d2wyja_: 2wyj A:

Lineage for d2wyja_ (2wyj A:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (166 PDB entries)

8. Domain d2wyja_: 2wyj A: [169698]
   Other proteins in same PDB: d2wyjb_
   automated match to d1c5md_
   complexed with 898

Details for d2wyja_

PDB Entry: 2wyj, 2.38 Å

PDB Description: structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with monoaryl p4 motifs

PDB Compounds: (A:) activated factor xa heavy chain

SCOPe Domain Sequences for d2wyja_:

Sequence, based on SEQRES records:

>d2wyja_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk

Sequence, based on observed residues (ATOM records):

>d2wyja_ b.47.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtqk
tgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacqg
dsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk

Timeline for d2wyja_:

• d2wyja_ first appeared in SCOPe 2.01
  
• d2wyja_ appears in SCOPe 2.06
  
• d2wyja_ appears in the current release, SCOPe 2.08