Lineage for d2wpaa_ (2wpa A:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674493Domain d2wpaa_: 2wpa A: [169539]
    Other proteins in same PDB: d2wpab1, d2wpab2, d2wpad1, d2wpad2
    automated match to d1vywa_
    complexed with 889, so4

Details for d2wpaa_

PDB Entry: 2wpa (more details), 2.51 Å

PDB Description: optimisation of 6,6-dimethyl pyrrolo 3,4-c pyrazoles: identification of pha-793887, a potent cdk inhibitor suitable for intravenous dosing
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wpaa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2wpaa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
plvdmenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllk
elnhpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqgla
fchshrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillg
ckyystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdy
kpsfpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl
rl

SCOPe Domain Coordinates for d2wpaa_:

Click to download the PDB-style file with coordinates for d2wpaa_.
(The format of our PDB-style files is described here.)

Timeline for d2wpaa_: