Lineage for d2wpaa1 (2wpa A:1-298)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2545120Protein automated matches [190091] (18 species)
    not a true protein
  7. 2545220Species Human (Homo sapiens) [TaxId:9606] [188447] (733 PDB entries)
  8. 2545695Domain d2wpaa1: 2wpa A:1-298 [169539]
    Other proteins in same PDB: d2wpaa2, d2wpab1, d2wpab2, d2wpac2, d2wpad1, d2wpad2
    automated match to d1vywa_
    complexed with 889, so4

Details for d2wpaa1

PDB Entry: 2wpa (more details), 2.51 Å

PDB Description: optimisation of 6,6-dimethyl pyrrolo 3,4-c pyrazoles: identification of pha-793887, a potent cdk inhibitor suitable for intravenous dosing
PDB Compounds: (A:) Cell division protein kinase 2

SCOPe Domain Sequences for d2wpaa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2wpaa1 d.144.1.7 (A:1-298) automated matches {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d2wpaa1:

Click to download the PDB-style file with coordinates for d2wpaa1.
(The format of our PDB-style files is described here.)

Timeline for d2wpaa1: