Lineage for d2wkza_ (2wkz A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2058816Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2058832Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2059056Species Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d) [TaxId:11683] [189173] (1 PDB entry)
  8. 2059057Domain d2wkza_: 2wkz A: [169425]
    automated match to d1ajva_
    complexed with 5ah

Details for d2wkza_

PDB Entry: 2wkz (more details), 1.7 Å

PDB Description: HIV-1 Protease Inhibitors Containing a Tertiary Alcohol in the Transition-State Mimic with Improved Cell-Based Antiviral Activity
PDB Compounds: (A:) Protease

SCOPe Domain Sequences for d2wkza_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2wkza_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 (isolate z2/cdc-z34 group m subtype d) [TaxId: 11683]}
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

SCOPe Domain Coordinates for d2wkza_:

Click to download the PDB-style file with coordinates for d2wkza_.
(The format of our PDB-style files is described here.)

Timeline for d2wkza_: