Lineage for d2wd2a_ (2wd2 A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2401367Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  4. 2401368Superfamily b.74.1: Carbonic anhydrase [51069] (2 families) (S)
  5. 2401369Family b.74.1.1: Carbonic anhydrase [51070] (2 protein domains)
    automatically mapped to Pfam PF00194
  6. 2401370Protein Carbonic anhydrase [51071] (10 species)
  7. 2401409Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (704 PDB entries)
    Uniprot P00918
  8. 2401545Domain d2wd2a_: 2wd2 A: [169241]
    automated match to d1cana_
    complexed with fmt, ms5, zn

Details for d2wd2a_

PDB Entry: 2wd2 (more details), 1.49 Å

PDB Description: a chimeric microtubule disruptor with efficacy on a taxane resistant cell line
PDB Compounds: (A:) Carbonic anhydrase 2

SCOPe Domain Sequences for d2wd2a_:

Sequence, based on SEQRES records: (download)

>d2wd2a_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprg
llpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplknrqikasfk

Sequence, based on observed residues (ATOM records): (download)

>d2wd2a_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghafnvefddavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhwntk
ygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgllpe
sldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdnwrp
aqplknrqikasfk

SCOPe Domain Coordinates for d2wd2a_:

Click to download the PDB-style file with coordinates for d2wd2a_.
(The format of our PDB-style files is described here.)

Timeline for d2wd2a_: