Lineage for d1fyhd2 (1fyh D:201-324)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2315782Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2315783Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2316095Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
    contains an additional helix in one of the crossover connections
  6. 2316133Protein Interferon-gamma [47318] (3 species)
    intertwined dimer
  7. 2316141Species Human (Homo sapiens) [TaxId:9606] [47320] (5 PDB entries)
  8. 2316145Domain d1fyhd2: 1fyh D:201-324 [16910]
    Other proteins in same PDB: d1fyhb1, d1fyhb2, d1fyhe1, d1fyhe2
    a single-chain variant
    complexed with cl

Details for d1fyhd2

PDB Entry: 1fyh (more details), 2.04 Å

PDB Description: 1:1 complex between an interferon gamma single-chain variant and its receptor
PDB Compounds: (D:) interferon gamma

SCOPe Domain Sequences for d1fyhd2:

Sequence, based on SEQRES records: (download)

>d1fyhd2 a.26.1.3 (D:201-324) Interferon-gamma {Human (Homo sapiens) [TaxId: 9606]}
sgefvkeaenlkkyfnaghsdvadngtlflgilknwkeesdrkimqsqivsfyfklfknf
kddqsiqksvetikedmnvkffnsnkkkrddfekltnysvtdlnvqrkaiheliqvmael
spaa

Sequence, based on observed residues (ATOM records): (download)

>d1fyhd2 a.26.1.3 (D:201-324) Interferon-gamma {Human (Homo sapiens) [TaxId: 9606]}
sgefvkeaenlkkyfngtlflgilknwkeesdrkimqsqivsfyfklfknfkddqsiqks
vetikedmnvkffnsnkkkrddfekltnysvtdlnvqrkaiheliqvmaelspaa

SCOPe Domain Coordinates for d1fyhd2:

Click to download the PDB-style file with coordinates for d1fyhd2.
(The format of our PDB-style files is described here.)

Timeline for d1fyhd2: