SCOPe 2.04: Domain d2w5ha_: 2w5h A:

Lineage for d2w5ha_ (2w5h A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)

8. Domain d2w5ha_: 2w5h A: [169065]
   automated match to d2java1

Details for d2w5ha_

PDB Entry: 2w5h, 2.33 Å

PDB Description: human nek2 kinase apo

PDB Compounds: (A:) serine/threonine-protein kinase nek2

SCOPe Domain Sequences for d2w5ha_:

Sequence, based on SEQRES records:

>d2w5ha_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrsdgghtvlhrdlkpanvfldgkqnvklgdfglarilnhdtsfakafvgtpyy
mspeqmnrmsyneksdiwslgcllyelcalmppftafsqkelagkiregkfrripyrysd
elneiitrmlnlkdyhrpsveeilenplilehhhhhh

Sequence, based on observed residues (ATOM records):

>d2w5ha_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sraedyevlytigtgsygrcqkirrksdgkilvwkeldygsmteaekqmlvsevnllrel
khpnivryydriidrtnttlyivmeyceggdlasvitkgtkerqyldeefvlrvmtqltl
alkechrrshrdlkpanvfldgkqnvklgdfglarhdtsfakafvgtpyymspeqmnsyn
eksdiwslgcllyelcalmppftafsqkelagkiregkfrripyrysdelneiitrmlnl
kdyhrpsveeilenplilehhhhhh

Timeline for d2w5ha_:

• d2w5ha_ first appeared in SCOPe 2.01
  
• d2w5ha_ appears in SCOPe 2.03
  
• d2w5ha_ appears in SCOPe 2.05
  
• d2w5ha_ appears in the current release, SCOPe 2.08, called d2w5ha1