Lineage for d1rh2b_ (1rh2 B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991750Protein Interferon-alpha 2b [47312] (1 species)
  7. 1991751Species Human (Homo sapiens) [TaxId:9606] [47313] (1 PDB entry)
  8. 1991753Domain d1rh2b_: 1rh2 B: [16894]
    CA-atoms only
    complexed with zn

Details for d1rh2b_

PDB Entry: 1rh2 (more details), 2.9 Å

PDB Description: recombinant human interferon-alpha 2b
PDB Compounds: (B:) interferon-alpha 2b

SCOPe Domain Sequences for d1rh2b_:

Sequence, based on SEQRES records: (download)

>d1rh2b_ a.26.1.3 (B:) Interferon-alpha 2b {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1rh2b_ a.26.1.3 (B:) Interferon-alpha 2b {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1rh2b_:

Click to download the PDB-style file with coordinates for d1rh2b_.
(The format of our PDB-style files is described here.)

Timeline for d1rh2b_: