Lineage for d1vlk__ (1vlk -)

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 536620Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 536621Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 536777Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (8 proteins)
    contains an additional helix in one of the crossover connections
  6. 536824Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
    intertwined dimer, similar to interferon-gamma
  7. 536825Species Epstein-Barr virus [TaxId:10376] [47308] (1 PDB entry)
  8. 536826Domain d1vlk__: 1vlk - [16888]

Details for d1vlk__

PDB Entry: 1vlk (more details), 1.9 Å

PDB Description: structure of viral interleukin-10

SCOP Domain Sequences for d1vlk__:

Sequence; same for both SEQRES and ATOM records: (download)

>d1vlk__ a.26.1.3 (-) Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) {Epstein-Barr virus}

SCOP Domain Coordinates for d1vlk__:

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Timeline for d1vlk__: