Lineage for d1inra_ (1inr A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991729Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 protein domains)
    contains an additional helix in one of the crossover connections
  6. 1991795Protein Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) [47306] (3 species)
    intertwined dimer, similar to interferon-gamma
  7. 1991800Species Human (Homo sapiens) [TaxId:9606] [47307] (6 PDB entries)
  8. 1991805Domain d1inra_: 1inr A: [16887]

Details for d1inra_

PDB Entry: 1inr (more details), 2 Å

PDB Description: cytokine synthesis
PDB Compounds: (A:) interleukin-10

SCOPe Domain Sequences for d1inra_:

Sequence, based on SEQRES records: (download)

>d1inra_ a.26.1.3 (A:) Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1inra_ a.26.1.3 (A:) Interleukin-10 (cytokine synthesis inhibitory factor, CSIF) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1inra_:

Click to download the PDB-style file with coordinates for d1inra_.
(The format of our PDB-style files is described here.)

Timeline for d1inra_: