SCOPe 2.02: Domain d2vgia3: 2vgi A:440-573

Lineage for d2vgia3 (2vgi A:440-573)

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.49: Pyruvate kinase C-terminal domain-like [52934] (2 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145, strand 5 is antiparallel to the rest

4. Superfamily c.49.1: PK C-terminal domain-like [52935] (2 families)

5. Family c.49.1.1: Pyruvate kinase, C-terminal domain [52936] (1 protein)

6. Protein Pyruvate kinase, C-terminal domain [52937] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82431] (4 PDB entries)

8. Domain d2vgia3: 2vgi A:440-573 [168578]
   Other proteins in same PDB: d2vgia1, d2vgia2, d2vgib1, d2vgib2, d2vgic1, d2vgic2, d2vgid1, d2vgid2
   complexed with fbp, k, mn, pga; mutant

Details for d2vgia3

PDB Entry: 2vgi, 2.87 Å

PDB Description: human erythrocyte pyruvate kinase: r486w mutant

PDB Compounds: (A:) pyruvate kinase isozymes r/l

SCOPe Domain Sequences for d2vgia3:

Sequence; same for both SEQRES and ATOM records:

>d2vgia3 c.49.1.1 (A:440-573) Pyruvate kinase, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
elrraaplsrdptevtaigaveaafkccaaaiivltttgrsaqllswyrpraaviavtrs
aqaarqvhlcrgvfpllyreppeaiwaddvdrrvqfgiesgklrgflrvgdlvivvtgwr
pgsgytnimrvlsi

Timeline for d2vgia3:

• d2vgia3 first appeared in SCOPe 2.01
  
• d2vgia3 appears in SCOPe 2.03
  
• d2vgia3 appears in the current release, SCOPe 2.08