SCOPe 2.06: Domain d2vekb_: 2vek B:

Lineage for d2vekb_ (2vek B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.1: Triosephosphate isomerase (TIM) [51351] (2 families)

5. Family c.1.1.1: Triosephosphate isomerase (TIM) [51352] (2 proteins)
   automatically mapped to Pfam PF00121

6. Protein Triosephosphate isomerase [51353] (20 species)

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [51357] (41 PDB entries)

8. Domain d2vekb_: 2vek B: [168490]
   automated match to d1dkwa_
   complexed with asf, cit, tbu; mutant

Details for d2vekb_

PDB Entry: 2vek, 1.6 Å

PDB Description: structure-based enzyme engineering efforts with an inactive monomeric tim variant: the importance of a single point mutation for generating an active site with suitable binding properties

PDB Compounds: (B:) triosephosphate isomerase

SCOPe Domain Sequences for d2vekb_:

Sequence; same for both SEQRES and ATOM records:

>d2vekb_ c.1.1.1 (B:) Triosephosphate isomerase {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
skpqpiaaanwksgspdslselidlfnstsinhdvqcvvastfvhlamtkerlshpkfvi
aaqnagnadalaslkdfgvnwivlghserrwyygetneivadkvaaavasgfmviacige
tlqeresgrtavvvltqiaaiakklkkadwakvviayepvwaigtgkvatpqqaqeahal
irswvsskigadvagelrilyggsvngknartlyqqrdvngflaglkpefvdiikatq

Timeline for d2vekb_:

• d2vekb_ first appeared in SCOPe 2.01
  
• d2vekb_ appears in SCOPe 2.05
  
• d2vekb_ appears in SCOPe 2.07
  
• d2vekb_ appears in the current release, SCOPe 2.08