Lineage for d1ax8a_ (1ax8 A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991438Family a.26.1.1: Long-chain cytokines [47267] (10 protein domains)
  6. 1991492Protein Leptin (obesity protein) [47282] (1 species)
  7. 1991493Species Human (Homo sapiens) [TaxId:9606] [47283] (1 PDB entry)
  8. 1991494Domain d1ax8a_: 1ax8 A: [16844]

Details for d1ax8a_

PDB Entry: 1ax8 (more details), 2.4 Å

PDB Description: Human obesity protein, leptin
PDB Compounds: (A:) obesity protein

SCOPe Domain Sequences for d1ax8a_:

Sequence, based on SEQRES records: (download)

>d1ax8a_ a.26.1.1 (A:) Leptin (obesity protein) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1ax8a_ a.26.1.1 (A:) Leptin (obesity protein) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1ax8a_:

Click to download the PDB-style file with coordinates for d1ax8a_.
(The format of our PDB-style files is described here.)

Timeline for d1ax8a_: