SCOP 1.59: Domain d1cnt4_: 1cnt 4:

Lineage for d1cnt4_ (1cnt 4:)

1. Root: SCOP 1.59

2. Class a: All alpha proteins [46456] (151 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)

4. Superfamily a.26.1: 4-helical cytokines [47266] (3 families)

5. Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)

6. Protein Ciliary neurotrophic factor (CNTF) [47280] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47281] (1 PDB entry)

8. Domain d1cnt4_: 1cnt 4: [16843]

Details for d1cnt4_

PDB Entry: 1cnt, 2.4 Å

PDB Description: ciliary neurotrophic factor

SCOP Domain Sequences for d1cnt4_:

Sequence, based on SEQRES records:

>d1cnt4_ a.26.1.1 (4:) Ciliary neurotrophic factor (CNTF) {Human (Homo sapiens)}
hrrdlcsrsiwlarkirsdltaltesyvkhqglnkninldsadgmpvastdqwselteae
rlqenlqayrtfhvllarlledqqvhftptegdfhqaihtlllqvaafayqieelmille
ykiprneadgmpinvgdgglfekklwglkvlqelsqwtvrsihdlrfis

Sequence, based on observed residues (ATOM records):

>d1cnt4_ a.26.1.1 (4:) Ciliary neurotrophic factor (CNTF) {Human (Homo sapiens)}
hrrdlcsrsiwlarkirsdltaltesyvkhqglelteaerlqenlqayrtfhvllarlle
dqqegdfhqaihtlllqvaafayqieelmilleykiprnkklwglkvlqelsqwtvrsih
dlrfis

Timeline for d1cnt4_:

• d1cnt4_ first appeared (with stable ids) in SCOP 1.55
  
• d1cnt4_ appears in SCOP 1.57
  
• d1cnt4_ appears in SCOP 1.61
  
• d1cnt4_ appears in the current release, SCOPe 2.08