Lineage for d2v5xb_ (2v5x B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2873861Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456
  4. 2873862Superfamily c.42.1: Arginase/deacetylase [52768] (3 families) (S)
  5. 2874190Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
    automatically mapped to Pfam PF00850
  6. 2874235Protein automated matches [190786] (1 species)
    not a true protein
  7. 2874236Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)
  8. 2874293Domain d2v5xb_: 2v5x B: [168360]
    automated match to d1t64a_
    complexed with k, v5x, zn

Details for d2v5xb_

PDB Entry: 2v5x (more details), 2.25 Å

PDB Description: crystal structure of hdac8-inhibitor complex
PDB Compounds: (B:) Histone deacetylase 8

SCOPe Domain Sequences for d2v5xb_:

Sequence, based on SEQRES records: (download)

>d2v5xb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khv

Sequence, based on observed residues (ATOM records): (download)

>d2v5xb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegieyglgydcpategifdyaaaiggatitaaqclidgmckvainwsgg
whhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvsl
hkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkav
vlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltg
vilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhv

SCOPe Domain Coordinates for d2v5xb_:

Click to download the PDB-style file with coordinates for d2v5xb_.
(The format of our PDB-style files is described here.)

Timeline for d2v5xb_: