SCOPe 2.08: Domain d2v5xb_: 2v5x B:

Lineage for d2v5xb_ (2v5x B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (41 PDB entries)

8. Domain d2v5xb_: 2v5x B: [168360]
   automated match to d1t64a_
   complexed with k, v5x, zn

Details for d2v5xb_

PDB Entry: 2v5x, 2.25 Å

PDB Description: crystal structure of hdac8-inhibitor complex

PDB Compounds: (B:) Histone deacetylase 8

SCOPe Domain Sequences for d2v5xb_:

Sequence, based on SEQRES records:

>d2v5xb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khv

Sequence, based on observed residues (ATOM records):

>d2v5xb_ c.42.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegieyglgydcpategifdyaaaiggatitaaqclidgmckvainwsgg
whhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvsl
hkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkav
vlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltg
vilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhv

Timeline for d2v5xb_:

• d2v5xb_ first appeared in SCOPe 2.01
  
• d2v5xb_ appears in SCOPe 2.07