Lineage for d1gnca1 (1gnc A:2-175)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2705447Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2705448Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2705449Family a.26.1.1: Long-chain cytokines [47267] (10 proteins)
  6. 2705456Protein Granulocyte-colony stimulating factor (G-CSF) [47268] (3 species)
  7. 2705463Species Human (Homo sapiens) [TaxId:9606] [47269] (4 PDB entries)
  8. 2705473Domain d1gnca1: 1gnc A:2-175 [16821]
    Other proteins in same PDB: d1gnca2

Details for d1gnca1

PDB Entry: 1gnc (more details)

PDB Description: structure and dynamics of the human granulocyte colony-stimulating factor determined by nmr spectroscopy. loop mobility in a four-helix- bundle protein
PDB Compounds: (A:) granulocyte colony-stimulating factor

SCOPe Domain Sequences for d1gnca1:

Sequence, based on SEQRES records: (download)

>d1gnca1 a.26.1.1 (A:2-175) Granulocyte-colony stimulating factor (G-CSF) {Human (Homo sapiens) [TaxId: 9606]}
tplgpasslpqsfllkcleqvrkiqgdgaalqeklvsecatyklchpeelvllghslgip
waplsscpsqalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfatti
wqqmeelgmapalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp

Sequence, based on observed residues (ATOM records): (download)

>d1gnca1 a.26.1.1 (A:2-175) Granulocyte-colony stimulating factor (G-CSF) {Human (Homo sapiens) [TaxId: 9606]}
tplgpasslpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwap
lsscpsqalqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqq
meelgmapalqptqgampafasafqrraggvlvashlqsflevsyrvlrhlaqp

SCOPe Domain Coordinates for d1gnca1:

Click to download the PDB-style file with coordinates for d1gnca1.
(The format of our PDB-style files is described here.)

Timeline for d1gnca1:

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Domains from same chain:
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d1gnca2