SCOPe 2.04: Domain d2uw6a_: 2uw6 A:

Lineage for d2uw6a_ (2uw6 A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (13 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [187007] (27 PDB entries)

8. Domain d2uw6a_: 2uw6 A: [168190]
   automated match to d1cmke_
   complexed with gvo

Details for d2uw6a_

PDB Entry: 2uw6, 2.23 Å

PDB Description: structure of pka-pkb chimera complexed with (s)-2-(4-chloro-phenyl)-2-(4-1h-pyrazol-4-yl)-phenyl)-ethylamine

PDB Compounds: (A:) cAMP-dependent protein kinase, alpha-catalytic subunit

SCOPe Domain Sequences for d2uw6a_:

Sequence; same for both SEQRES and ATOM records:

>d2uw6a_ d.144.1.7 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
svkeflakakedflkkwenpaqntahldqferiktlgtgsfgrvmlvkhmetgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpfltklefsfkdnsnlymvmeyapggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenlmidqqgyikvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfkgpgdtsnfddyeeeeirvsinekcgkefsef

Timeline for d2uw6a_:

• d2uw6a_ first appeared in SCOPe 2.01
  
• d2uw6a_ appears in SCOPe 2.03
  
• d2uw6a_ appears in SCOPe 2.05
  
• d2uw6a_ appears in the current release, SCOPe 2.08