Lineage for d2rhrb1 (2rhr B:1-261)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2102557Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2102558Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2102904Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2103151Protein beta-keto acyl carrier protein reductase [51788] (8 species)
  7. 2103180Species Streptomyces coelicolor [TaxId:1902] [117408] (8 PDB entries)
    Uniprot P16544 #SP
  8. 2103196Domain d2rhrb1: 2rhr B:1-261 [168128]
    Other proteins in same PDB: d2rhrb2
    automated match to d1w4zb_
    complexed with emo, ndp; mutant

Details for d2rhrb1

PDB Entry: 2rhr (more details), 2.5 Å

PDB Description: p94l actinorhodin ketordeuctase mutant, with nadph and inhibitor emodin
PDB Compounds: (B:) Actinorhodin Polyketide Ketoreductase

SCOPe Domain Sequences for d2rhrb1:

Sequence, based on SEQRES records: (download)

>d2rhrb1 c.2.1.2 (B:1-261) beta-keto acyl carrier protein reductase {Streptomyces coelicolor [TaxId: 1902]}
matqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgr
tcdvrsvpeiealvaavverygpvdvlvnnagrlgggataeladelwldvvetnltgvfr
vtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgi
tvnavcpgfvetpmaasvrehysdiwevsteeafdritarvpigryvqpsevaemvayli
gpgaaavtaqalnvcgglgny

Sequence, based on observed residues (ATOM records): (download)

>d2rhrb1 c.2.1.2 (B:1-261) beta-keto acyl carrier protein reductase {Streptomyces coelicolor [TaxId: 1902]}
matqdsevalvtgatsgigleiarrlgkeglrvfvcargeeglrttlkelreagveadgr
tcdvrsvpeiealvaavverygpvdvlvnnagrlgggataeladelwldvvetnltgvfr
vtkqvlkaggmlergtgrivniastggkqgvvhaapysaskhgvvgftkalglelartgi
tvnavcpgfvetpmaasvrehteeafdritarvpigryvqpsevaemvayligpgaaavt
aqalnvcgglgny

SCOPe Domain Coordinates for d2rhrb1:

Click to download the PDB-style file with coordinates for d2rhrb1.
(The format of our PDB-style files is described here.)

Timeline for d2rhrb1:

View in 3D
Domains from same chain:
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d2rhrb2
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Domains from other chains:
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d2rhra_