SCOP 1.73: Domain d1rhga_: 1rhg A:

Lineage for d1rhga_ (1rhg A:)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)

6. Protein Granulocyte-colony stimulating factor (G-CSF) [47268] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47269] (5 PDB entries)

8. Domain d1rhga_: 1rhg A: [16812]

Details for d1rhga_

PDB Entry: 1rhg, 2.2 Å

PDB Description: the structure of granulocyte-colony-stimulating factor and its relationship to those of other growth factors

PDB Compounds: (A:) granulocyte colony-stimulating factor

SCOP Domain Sequences for d1rhga_:

Sequence, based on SEQRES records:

>d1rhga_ a.26.1.1 (A:) Granulocyte-colony stimulating factor (G-CSF) {Human (Homo sapiens) [TaxId: 9606]}
lpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwaplsscpsqa
lqlagclsqlhsglflyqgllqalegispelgptldtlqldvadfattiwqqmeelgmap
alqptqgampafasafqrraggvlvashlqsflevsyrvlrhla

Sequence, based on observed residues (ATOM records):

>d1rhga_ a.26.1.1 (A:) Granulocyte-colony stimulating factor (G-CSF) {Human (Homo sapiens) [TaxId: 9606]}
lpqsfllkcleqvrkiqgdgaalqeklcatyklchpeelvllghslgipwapllagclsq
lhsglflyqgllqalegispelgptldtlqldvadfattiwqqmeelgmmpafasafqrr
aggvlvashlqsflevsyrvlrhla

Timeline for d1rhga_:

• d1rhga_ first appeared (with stable ids) in SCOP 1.55
  
• d1rhga_ appears in SCOP 1.71
  
• d1rhga_ appears in SCOP 1.75
  
• d1rhga_ appears in the current release, SCOPe 2.08